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Soman (3,3-dimethylbutan-2-yl methylphosphonofluoridate) has a highly branched alkoxyl group and is one of the most lethal nerve agents with an aging half-life of 4.62 min and 1.87 min at pH 7 when bound with TcAChE 30 and HuBChE 31 respectively. Soman has two chiral centers, namely the P and Cα atoms and the stereochemistry of the P atom is inverted once a covalent adduct is formed between 32.


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Slow or fast heart rate. Small, pinpoint pupils. Watery eyes. Weakness. Even a tiny drop of nerve agent on the skin can cause sweating and muscle twitching where the agent touched the skin. Exposure to a large dose of soman by any route may result in these additional adverse health effects: Convulsions.


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Facts About Soman. Overview of soman, including signs & symptoms, protection, & treatment. Case Definition: Nerve Agents or Organophosphates. Includes clinical description, lab criteria for diagnosis, & case classification. Emergency Response Card: Information for First Responders. Agent-specific identification, medical symptoms, prevention.


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March 7, 2003 Page 1 of 5 FACT SHEET Facts About Soman What soman is • Soman is a human-made chemical warfare agent classified as a nerve agent.


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By ABC News. April 7, 2003, 10:58 AM. -- Soman, a nerve agent said to have made up much of the former Soviet Union's chemical arsenal, is considered one of the most toxic chemical agents known.


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The user should verify compliance of the cards with the relevant STATE or TERRITORY legislation before use. NIOSH, CDC 2003. Soman (military designation GD) is one of the nerve agents, which are the most toxic of the known chemical warfare agents. It has an odor like camphor or rotting fruit. Exposure to soman can cause death in minutes.


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The experimental pathophysiology of organophosphorus (OP) chemical exposure has been extensively reported. Here, we describe an altered fecal bacterial biota and urine metabolome following intoxication with soman, a lipophilic G class chemical warfare nerve agent.


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Volume 149, number 1 FEBS LETTERS November 1982 Quantification of the organophosphorus nerve agent soman by competitive inhibition enzyme immunoassay using monoclonal antibody


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Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: SMALL FIRE: Dry chemical, CO2 or water spray. LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal.


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Soman (or GD, EA 1210, Zoman, PFMP, A-255, systematic name: O-pinacolyl methylphosphonofluoridate) is an extremely toxic chemical substance. It is a nerve agent, interfering with normal functioning of the mammalian nervous system by inhibiting the enzyme cholinesterase.It is an inhibitor of both acetylcholinesterase and butyrylcholinesterase. As a chemical weapon, it is classified as a weapon.


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The primary aim of this work is to provide relative response factors [25] (RRFs) as target-based standards, referred to in this study as focusing agents, for G-series agents and sulfur mustard quantification after analyzed by two different HAPSITE® ER systems.Our previous work shows system-level improvement in the data quality when switching from external and internal standards to in-situ.


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The half-life of soman in water at pH 7, 20 °C and 30 °C has been reported as 82 and 22 hours, respectively; the half-life of soman in water at pH 7.6, 20 and 30 °C has been reported as 41 and 9.6 hours, respectively (3). At a pH >10, hydrolysis to PMPA occurs within a few minutes (4).


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Preface. This report assesses the potential non-cancer and cancer effects of chemical agent GD (CAS No. 96-64-0). This document supports the activities of the Material/Chemical Risk Assessment Working Group of the Environmental Risk Assessment Program, a cooperative endeavor of the Department of Defense, Department of Energy, and Environmental Protection Agency.


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NRT Quick Reference Guide: Soman (GD) QRGs are intended for Federal OSC/RPMs [July 2022 Update (nrt.org): replaced previous version dated January 2015] Page 2 of 10 4.2. Signs/Symptoms: Initial symptoms will vary depending on dose and exposure route. The following is a general list of possible symptoms. The severity of effects depends upon the dosage.


Investigating Extended ShelfLife of Soman Nerve Agent PreTreatment CBRNE Central

NMR titration studies in acetonitrile-d3/DMSO-d6 mixtures demonstrate that diindolylurea-based receptors can form complexes with the organophosphorus nerve agent soman in organic solution.