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puerarin. Puerarin is the major bioactive ingredient isolated from the root of the Pueraria lobata (Willd.) Ohwi, which is well known as Gegen (Chinese name) in traditional Chinese medicine. As the most abundant secondary metabolite, puerarin was isolated from Gegen in the late 1950s. Since then, its pharmaco..
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Puerarin, an isoflavone glycoside derived from Pueraria lobata (Willd.) Ohwi, has been identified as a pharmacologically active component with diverse benefits. A large number of experimental and clinical studies have demonstrated that puerarin is widely used in the treatment of a variety of diseases. Among them, cardiovascular diseases (CVDs.
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Harga Puerarin - Bagaimana Bahaya Dan Efek Samping Puerarin . Puerarin ramuan pembesar buah dada yang aman dan berstandart GMP mungkin Anda bisa memperolehnya di apotik dan toko obat. Namun perhatikan tidak semuanya menjual produk ori, untuk jaga-jaga tentukanlah pedagang yang terpercaya ataupun hubungi Customer Service Kita.
Pueraria mirifica extract / puerarin
Up to now, puerarin has been widely proven to have pharmacological activities such as vasodilator, anti-inflammatory, antioxidant, anti-apoptotic, regulating autophagy, anti-insulin resistance, anti-cancer, etc. It has protective effects on cell damage caused by pathological factors and has shown good efficacy in the treatment of various diseases (Ma et al., 2022).
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Puerarin is a C-glucoside of the isoflavone daidzein extracted from Pueraria. It has been widely investigated to explore its therapeutic role in eye diseases and the molecular mechanisms. Purpose: To collect the available literature from 2000 to 2022 on puerarin in the treatment of ocular diseases and suggest the future required directions to.
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Puerarin—an isoflavone with beneficial effects on bone health
Puerarin is the main active component extracted from kudzu root, and its structural formula is 8-β-D-grapes pyranose-4, 7-dihydroxy isoflavone, with a white needle crystal; it is slightly soluble in water, and its aqueous solution is colorless or light yellow. Puerarin is a natural antioxidant with high health value and has a series of.
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Puerarin derivative P1-EA and P2-EA were formed by substitution of the original phenolic hydroxyl in the puerarin molecules, which had higher lipophilicity and thus better permeabilized through the blood-brain barrier as compared to puerarin. It was resulted in an enhancement of protective activity against cerebral ischemic damage in a mouse.
Puerarin reduces ischemia/reperfusioninduced myocardial injury in diabetic rats via
Puerarin, a chemotaxonomic marker of Pueraria, received investigational drug status for the treatment of alcohol abuse and listed in DRUGBANK database. The purpose of this review is to provide insights on health benefits of Pueraria, its bioactive constituents and molecular mechanisms. The information is retrieved from various databases.
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Puerarin, also called daidzein-8-c-glucoside (7,4'-dihydroxy-8-c-glycosylisoflavone), is an isoflavone compound isolated from Pueraria lobata (Fig. 1).As one of the important flavonoids, puerarin has unique physicochemical properties [33].Due to the stereo-hindrance of C-cyclopyranyl group, puerarin molecules easily form large conjugate systems, which tend to be flat in space, and thus, its.
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Puerarin has shown unique pharmacological effects on myocardial ischemia (MI). Changing the crystal form is an effective approach to improve the cardioprotective effects of puerarin. However, the.
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The antihyperglycemic action of puerarin, purified from the roots of Pueraria lobata, was investigated in streptozotocin-induced diabetic rats (STZ-diabetic rats). Bolus intravenous injection of puerarin decreased the plasma glucose concentrations in a dose-dependent manner in STZ-diabetic rats. Similar treatment with puerarin also decreased.
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Puerarin is an isoflavone compound extracted from the root of Pueraria lobata and has pharmacological effects such as dilating cerebral vessels and anti-free radical generation in cerebral ischemic tissues. With the deepening of experimental research and clinical research on puerarin, it has been found that puerarin has a protective effect on.
Pueraria mirifica extract / puerarin Goutte d’amour
2.1. Obesity, metabolic syndrome, and diabetes mellitus. Obesity, metabolic syndrome, and diabetes mellitus are major risk factors for the initiation and progression of cardiovascular and cerebrovascular diseases and are dramatically increased with advancing age in modern society. 12 In obese mice treated with puerarin for 8 months, circulating levels of isoflavone metabolites were.
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Puerarin is mainly used to treat eye diseases by ocular administration and systemic administration. Puerarin has poor water and lipid solubility. Its solubility in water is 0.46 mg/ml, and in phosphate buffer at pH 7.4 is 7.56 mg/ml. Therefore, puerarin has poor oral absorption and low bioavailability.
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1. Introduction. Puerarin is the main active constituent isolated from the root of the Pueraria lobata (Willd.)Ohwi (Fabaceae), which is native to Southeast Asia and widely known as Gegen in traditional Chinese medicine. As one of the earliest known Chinese medicinal herbs in China, Gegen is frequently used to treat a wide range of conditions including fever, pain, diabetes, gastrointestinal.