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Cogan's syndrome (also Cogan syndrome) is an uncommon disease seen mostly in young adults that can severely affect vision and hearing. [1] [2] This syndrome was described by Dr. David G Cogan from the Massachusetts Eye and Ear Infirmary in 1945 as a 'syndrome of nonsyphilitic interstitial keratitis and vestibuloauditory symptoms'. [3]
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Bookshelf ID: NBK580546 PMID: 35593853. Cogan syndrome (CS) is an autoimmune disease characterized by inflammation of the inner ears and the eyes, presenting with vestibulo-auditory dysfunction and interstitial keratitis. [1] The disease progresses over 3 to 90 days and usually shows a response to steroid treatment.
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Abstract. Cogan's syndrome (CS) is a rare disorder characterized by nonsyphilitic interstitial keratitis (IK) and audio-vestibular symptoms. CS affects mainly young Caucasian adults, mostly during their first three decades of age, and may develop into typical and atypical variants. Typical CS manifests primarily with IK and hearing loss.
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Cogan's syndrome is a rare disease, which primarily affects young adults; reports that establish the age of onset as ranging from 3 to 50 years have been published [ 9 ]. The average age of disease onset is 29 years. No gender predilection seems to exist in most of the literature series. In 25% of the patients, the eye and the ear can be.
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The Cogan syndrome is defined by the association of a non-syphilitic interstitial keratitis and a cochleovestibular involvement, with various visceral manifestations which can thus realize the picture of a systemic disease. Cogan syndrome is a very rare systemic disorder that affects young adults without gender predilection . Very few cases are.