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INDICATIONS AND USAGE. Amiodarone injection is an antiarrhythmic agent indicated for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation (VF) and hemodynamically unstable ventricular tachycardia (VT) in patients refractory to other therapy. ( 1) DOSAGE AND ADMINISTRATION.
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Lynne Kelly, Pharmacist, CCTC Brenda Morgan, Clinical Nurse Specialist, CCTC Last Update: September 21, 2020; Reviewed February 13, 2023 (BM)
Amiodarone injection calculation using syringe pump/Infusion pump.//Drug calculation for Nurses
Side Effects for Cordarone IV. In a total of 1836 patients in controlled and uncontrolled clinical trials, 14% of patients received Cordarone I.V. for at least 1 week, 5% received it for at least 2 weeks, 2% received it for at least 3 weeks, and 1% received it for more than 3 weeks, without an increased incidence of severe adverse reactions.
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Indications and Dosage. Intravenous. Supraventricular arrhythmias, Ventricular arrhythmias. Adult: Initially, 5 mg/kg via infusion over a period of 20-120 minutes, may repeat infusion up to 1,200 mg (approx 15 mg/kg) per 24 hours, with a rate of infusion adjusted based on clinical response. For emergency cases: 150-300 mg via slow inj over ≥3.
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Dosis Amiodarone. Obat amiodarone digunakan pada pasien dewasa dengan rincian dosis sebagai berikut [1]: → Dosis awal 5 mg/kg melalui infus selama 20-120 menit, dapat diulang infus hingga 1.200 mg (sekitar 15 mg/kg) per 24 jam, dengan kecepatan infus disesuaikan berdasarkan respon klinis.
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Intravenous amiodarone has interesting and complex pharmacokinetics. Peak serum concentrations after 15-minute infusions in healthy volunteers range from 5 to 41 mg/L. Peak levels after 150 mg of supplemental infusions in patients with VT/VF range between 7 and 26 mg/L. Because of the rapid distribution of this drug, serum concentrations.
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360 mg over the NEXT 6 hours (1 mg/min). Add 18 mL of amiodarone (900 mg) to 500 mL D 5 W (concentration = 1.8 mg/mL) Maintenance infusion. 540 mg over the REMAINING 18 hours (0.5 mg/min). Decrease the rate of the slow loading infusion to 0.5 mg/min. Table 2: AMIODARONE HYDROCHLORIDE SOLUTION STABILITY. Solution.
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Half-Life Elimination. Note: Half-life is shortened in children vs adults. Amiodarone: Single dose: 58 days (range: 15 to 142 days) Oral chronic therapy: Mean range: 40 to 55 days (range: 26 to 107 days) IV single dose: Mean range: 9 to 36 days. N-desethylamiodarone (active metabolite): Prolonged in severe left ventricular dysfunction.
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Selama atau setelah pemberian terapi amiodarone intravena, individu dapat dialihkan ke terapi amiodarone oral. Berikut dosis konversi oral dari amiodarone pada individu yang telah mendapatkan amiodarone intravena: Kurang dari 1 minggu infus IV: 800-1600 mg/ hari. 1-3 minggu infus IV: 600-800 mg/ hari. Lebih dari 3 minggu infus IV: 400 mg/ hari.
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Prescribe 900mg of amiodarone to be administered as a continuous infusion (ideally via a CVC). Dilute in a 500mL glucose 5% non-PVC fluid bag (free-flex bag. Available in ACC or the RHW AHDR). Administer via an infusion pump giving set over 24hours at a rate of 21mL/hour Follow with oral/IV dose as per Drs orders.
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Dalam resusitasi kardiopulmoner, amiodarone hydrochloride dapat bermula melalui injeksi intravena. Dosis awal adalah 300 mg pemberiannya melalui infus selama 20-60 menit. Jika membutuhkan, dosis tambahan sebesar 150 mg memberikannya melalui infus setelah 3-5 menit. 4. Dosis untuk pasien dengan gagal jantung.
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Dewasa: awalnya, 200 mg sebanyak 3 kali sehari selama 1 minggu kemudian dikurangi menjadi 200 mg tiap dua hari selama seminggu lagi. Dosis pemeliharaan sebanyak 200 mg setiap hari berdasarkan respons pasien. Lansia: gunakan dosis efektif minimum. Dosis di atas hanyalah pedoman umum terkait penggunaan obat ini.
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Amiodarone :Antiarrhythmic Agent INDICATIONLife-threatening ventricular arrhythmiasventricular tachycardia ventricular fibrillation.-----.
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Amiodarone injection side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.. Amiodarone takes a long time to completely clear from your body. You may continue to have side effects from amiodarone after you stop using it.
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Each 10ml pre-filled syringe contains 300mg amiodarone hydrochloride equivalent to 30mg amiodarone hydrochloride per ml. Excipients: Each pre-filled syringe contains112mg of iodine.
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Dosis awal 200 mg, 3 kali sehari, selama 1 Dosis selanjutnya dapat dikurangi menjadi 200 mg, 2 kali sehari. Dosis pemeliharaan bisa diturunkan tergantung pada respons tubuh pasien. Sementara itu, amiodarone bentuk suntik biasanya digunakan untuk gangguan irama jantung yang darurat, seperti fibrilasi ventrikel tanpa denyut nadi. Suntikan.