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Ketorolac may adversely affect fetal circulation and inhibit uterine contractions during labor and delivery, increasing risk of uterine hemorrhage.. (300 mcg/mL) may displace ketorolac from binding sites; ibuprofen, naproxen, or piroxicam does not alter the protein binding of ketorolac. Protein binding of NSAIAs reduced by aspirin, but.
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Ketorolac injection is used for the short-term relief of moderately severe pain in people who are at least 17 years of age. Ketorolac injection should not be used for longer than 5 days, for mild pain, or for pain from chronic (long-term) conditions. You will receive your first doses of ketorolac by intravenous (into a vein) or intramuscular.
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Comment: Coadministration with medications that cause fluid and electrolyte abnormalities may increase the risk of adverse events of seizure, arrhythmias, and renal impairment. sotalol and ketorolac both increase serum potassium. Use Caution/Monitor. ketorolac decreases effects of sotalol by pharmacodynamic antagonism.
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Pharmacology Source Indication. Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and has antipyretic, analgesic and anti-inflammatory properties. 2 It is indicated for short term management of acute pain that requires the calibre of pain management offered by opioids. 14 Clinicians may choose to initiate ketorolac to manage post-operative pain, spinal and soft tissue pain.
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The recommended dose for oral administration is 10 mg every 4 to 6 hours, not exceeding 40 mg per day. Common side effects include rash, ringing in the ears, headaches, dizziness, drowsiness, abdominal pain, nausea, diarrhea, constipation, heartburn, and fluid retention. Toradol, like most NSAIDs, is commonly associated with gastrointestinal.
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Ketorolac untuk ibu hamil dan menyusui: Kategori C (Trimester pertama dan kedua): Studi pada binatang percobaan memperlihatkan adanya efek samping terhadap janin, namun belum ada studi terkontrol pada wanita hamil. Obat hanya boleh digunakan jika besarnya manfaat yang diharapkan melebihi besarnya risiko terhadap janin.
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Apakah ketorolac aman untuk ibu hamil dan menyusui? U.S. Food and Drug Administration menggolongkan obat ini dalam kategori C, artinya studi pada hewan percobaan telah menunjukkan risiko efek samping pada janis. Namun, studi terkontrol pada wanita hamil masih belum memadai.
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Ketorolac (Toradol) is a prescription non-steroidal anti-inflammatory drug (NSAID).It provides pain relief by blocking certain chemicals in your body that cause pain and inflammation. But ketorolac (Toradol) is meant for short-term use only due to the risk for severe side effects, such as heart attack and stomach ulcers.Typically, ketorolac (Toradol) is first given as an injection in a.
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Jika ketorolac digunakan pada usia kehamilan 20-30 minggu, dapat mengakibatkan terjadinya oligohidramnion yang bisa menyebabkan gangguan fungsi ginjal janin. Bila harus menggunakan ketorolac, harap gunakan ketorolac dengan dosis efektif terendah dan dalam durasi sesingkat mungkin. [3,4] Ketorolac dapat didistribusikan dalam air susu ibu (ASI).
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Upset stomach, nausea, vomiting, constipation, diarrhea, gas, dizziness, or drowsiness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that.
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Ketorolac is a medication used in the management and treatment of acute moderate to severe pain. It is in the nonsteroidal anti-inflammatory drug class. This activity outlines the indications, actions, and contraindications for ketorolac as a valuable agent in treating acute pain. It will also highlight the mechanism of action, adverse event profile, and other key factors (e.g.
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Ketorolac is used to relieve moderately severe pain, usually pain that occurs after an operation or other painful procedure. It belongs to the group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs).. Ibuprofen (e.g., Motrin®) Indomethacin (e.g., Indocin®) Ketoprofen (e.g., Orudis®) Meclofenamate (e.g., Meclomen.
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This medicine may raise the risk of heart and blood vessel problems like heart attack and stroke. These effects can be deadly. The risk may be greater if you have heart disease or risks for heart disease. However, it can also be raised even if you do not have heart disease or risks for heart disease. The risk can happen within the first weeks.
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Belum ada penelitian yang memadai mengenai risiko penggunaan ketorolac pada ibu hamil dan menyusui. Namun, penggunaan obat mungkin tidak disarankan. Ketorolac berisiko dapat membahayakan janin dan menyebabkan masalah pada persalinan bila dikonsumsi di usia sekitar 20 minggu kehamilan. Konsumsi ketorolac kebanyakan tidak diperbolehkan setelah 20.
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The average amount of hydromorphone used in the ketorolac and ibuprofen arm was 3.68 (SD± 4.58) mg and 4.04 (SD± 4.97) mg respectively, p = 0.58. A sub-group analysis based on type of surgery showed decreased pain at rest (VAS 2.77 versus 4.88, p = 0.04), and increased satisfaction (VAS 1.69 versus 4.67, p = 0.003) in patients who had.
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For oral dosage form (tablets): For pain: Adults (patients 16 years of age and older)—One 10-milligram (mg) tablet four times a day, four to six hours apart. Some people may be directed to take two tablets for the first dose only. Children up to 16 years of age—Use and dose must be determined by your doctor. For injection dosage form: