SURGICEL™ Original Absorbable Hemostat Ethicon


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Surgicel is a hemostatic agent (blood-clot-inducing material) made of an oxidized cellulose polymer (polyanhydroglucuronic acid), manufactured by the Ethicon subsidiary of Johnson & Johnson.It was introduced into clinical practice in 1947. It is used to control bleeding, including post-surgical bleeding and bleeding from superficial injuries to the skin.


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1. MacDonald M. SURGICEL® Powder versus ARISTA™ AH. Final Report, PSE Accession No. 15-0120, Project No. 16438. September 2, 2015. Ethicon, Inc. 2. Surface energy/tension analysis among ORC Aggregate, ORC Fine Fiber, and Arista - Project PIXIE. Ethicon, Inc. 3. MacDonald M. Pivotal study comparing SURGICEL® Powder to SURGICEL® Original


SURGICEL™ Original Absorbable Hemostat Ethicon

Surgicel (Ethicon, Somerville, NJ) is a chemically sterilized material prepared through oxidation of regenerated alpha cellulose (oxycellulose). The basic element of Surgicel is polyanhydroglucuronic acid, which is spun into threads and then woven into gauze. Surgicel has a pH of 3. If the material is maintained in the wound for up to 120 days.


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Surgicel. Oxidized regenerated cellulose or Surgicel ® (Ethicon, part of Johnson & Johnson) 7 is a bioabsorbable sterile knitted fabric prepared by the controlled oxidation of regenerated cellulose.. The mechanism of action whereby Surgicel® accelerates clotting is not completely understood, the effect appears to be physical rather than an alteration to the physiological clotting mechanism.


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With 60 years of demonstrated safety and efficacy, 1-4 SURGICEL Original Absorbable Hemostat has paved the way for hemostasis control - marked by its loose knit material and made for continuous oozing bleeding. 5 It comes in a variety of sizes with added bactericidal properties. A2 A product from the SURGICEL Family of Absorbable Hemostats is used somewhere in the world every 2.1 seconds. 6


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Oxidized regenerated cellulose (Surgicel) Topical thrombin; Suture set; Dental forceps; Tea bag; Bone rongeur; Bone wax; Headlamp; Yankauer suction catheter; Suction source and tubing; Silver nitrate matchsticks; Electrocautery unit + + Explain the risks, benefits, potential complications, and aftercare to the patient and/or their.


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Objective Laparoscopic cholecystectomy is the first-choice treatment for symptomatic cholelithiasis. Though generally safe, this procedure is not without complications, with bleeding the most frequent cause of conversion to open cholecystectomy. Oxidized regenerated cellulose (ORC) added to conventional hemostatic strategies, is widely used to control bleeding during surgery despite limited.


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SURGICEL® Powder delivery device is now ready for use. Compress bellows using light pressure to apply powder to treatment site (Fig. 5). 5. As an approximate guide, one SURGICEL® Powder delivery device can provide coverage of 10.5 in2 (3.2 x 3.2 inch area) when applied in one layer at a distance of approximately 2


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Study Design. This was a prospective, single-arm, multicenter trial on the adjunctive use of SURGICEL®-P to control surgical hemorrhage (capillary, venous, or small arterial) for which conventional hemostatic methods (such as sutures, ligature, or electrocautery) were impractical or ineffective because of the anatomy or the tissue characteristics at the bleeding site (eg soft tissues with.


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The first and only absorbable hemostats proven bactericidal against a broad range of gram-positive and gram-negative organisms, including various antibiotic-resistant bacteria (MRSA, VRE, PRSP and MRSE) Proprietary oxidized regenerated cellulose (ORC) technology designed to ensure purity and consistency. Plant-based product.


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• SURGICEL Powder is an absorbable hemostat, and should not be used as an adhesion prevention product. • The SURGICEL Powder and the SURGICEL Endoscopic Applicator devices were not designed for intraluminal procedures. WARNINGS • SURGICEL Powder is not intended for use on dry (non-bleeding) surfaces or for prevention of bleeding.


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Penetration that gets to the source - for efficient hemostasis in broad-surface bleeds. A1-3 SURGICEL Powder, the latest in SURGICEL innovation, provides a unique, powdered structure that penetrates beyond the surface of a bleed - with no prep needed and a ready-to-use application. B4,5 Its unique design provides updated hemostatic technology alongside a legacy of SURGICEL family bactericidal.


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Surgicel ® is a cellulose-based product that is placed at the site of bleeding intraoperatively to promote hemostasis. This serves as a hemostatic adjunct in the control of local hemorrhage, although the exact mechanism of action is uncertain. When this material saturates with blood, it swells into a brownish or black gelatinous mass, which.


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Several potential mechanisms of action have been proposed for how Surgicel promotes hemostasis. 1,2 One possible mechanism is that Surgicel acts as a passive agent promoting clot formation by providing a physical scaffold around which platelets can aggregate forming a clot. Alternatively, it is possible that the breakdown of Surgicel produces an acidic environment and that the low pH.


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• SURGICEL Powder should not be used on non-hemorrhagic serous oozing surfaces, since body fluids other than whole blood, such as serum, do not react with SURGICEL® Powder to produce satisfactory hemostatic effect. • SURGICEL Powder is an absorbable hemostat, and should not be used as an adhesion prevention product.


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Oxidized regenerated cellulose (ORC) is a plant-based polymer, consisting of continuous fibers with mechanical hemostatic properties, that was first introduced as a hemostat in 1943 but is now available in various topical hemostatic formulations. 11,12 ORC provides a matrix for clot formation and enhances platelet activation and adhesion. In addition, because it creates a local acidic milieu.